Dynein Light Chain Tctex Type 1 Antibody (YA3263),MedChemexpress,HY-P83518

Dynein Light Chain Tctex Type 1 Antibody (YA3263) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Dynein Light Chain Tctex Type 1.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-F,IHC-P,ICC/IF,FC,IP

Conjugate

Non-conjugated

Platform ID

BAB145446229

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
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MedChemexpress

Master of Bioactive Molecules

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Email:

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Product Specifications
Scientific Background
Synonyms

Specifications

NameDynein Light Chain Tctex Type 1 Antibody (YA3263)
Cat. No.HY-P83518
Accession NumberP63172
Gene ID (Entrez)6993
HostRabbit
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-F,IHC-P,ICC/IF,FC,IP
Working DilutionsWB: 1:500-1:1000; IHC-P: 1:20-1:50; ICC/IF: 1:200-1:500; FC: 1:50-1:100; IP: 1:20-1:50
ClonalityRecombinant,Monoclonal
Clone NumberYA3263
Molecular WeightPredicted band size: 12 kDa; Observed band size: 12 kDa
ImmunogenRecombinant protein of human TCTEX-1
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The related gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by The related gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. The protein interacts with oncogenic nucleoporins to disrupt related gene regulation and cause leukemic transformation. Pseudorelated genes of The related gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

CW-1; TCTEL1; tctex-1

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