Dynein intermediate chain 1 Rabbit mAb,ABclonal,A3624

Reactivity

Mouse, Rat

Application

WB, ELISA

Conjugate

Unconjugated

Platform ID

BAB612562824

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDynein intermediate chain 1 Rabbit mAb
Cat. No.A3624
Accession NumberQ9UI46
Gene ID (Entrez)27019
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC2061
Molecular Weight79kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.

Synonyms

PCD; DIC1; ICS1; CILD1; Dynein intermediate chain 1

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