E cadherin Polyclonal Antibody, PE Conjugated,Bioss,bs-10009R-PE

Host

Rabbit

Reactivity

Human, Rat

Application

WB, FCM, IF(IHC-P), IF(IHC-F), IF(ICC)

Conjugate

PE

Platform ID

BAB352907288

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameE cadherin Polyclonal Antibody, PE Conjugated
Cat. No.bs-10009R-PE
Accession NumberP12830
Gene ID (Entrez)999
HostRabbit
IsotypeIgG
ReactivityHuman, Rat
ConjugationPE
ApplicationWB, FCM, IF(IHC-P), IF(IHC-F), IF(ICC)
Working DilutionsWB:1:300-5000 | FCM:1:20-100 | IF(IHC-P): | IF(IHC-F): | IF(ICC):
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

Synonyms

UVO; CDHE; ECAD; LCAM; Arc-1; CD324; Cadherin-1; CAM 12/8; Epithelial cadherin; E-cadherin; Uvomorulin; CDH1

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