E3 SUMO-Protein Ligase PIAS4 (PIAS4) Antibody,Abbexa,abx026852

Name: E3 SUMO-Protein Ligase PIAS4 (PIAS4) Antibody,Abbexa,abx026852
Brand: Buy Antibody
SKU: BAB647980988

PIASy1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway, the wnt pathway and the steroid hormone signaling pathway. PIASy1 is involved in gene silencing, and promotes PARK7 sumoylation.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB, IHC

Conjugate

Unconjugated

Platform ID

BAB647980988

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

NameE3 SUMO-Protein Ligase PIAS4 (PIAS4) Antibody

Cat. No.abx026852

Accession NumberQ8N2W9

HostRabbit

IsotypeIgG

ReactivityHuman

ConjugationUnconjugated

ApplicationELISA, WB, IHC

Working DilutionsWB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.

ClonalityPolyclonal

Molecular WeightCalculated MW: 56.5 kDa

ImmunogenKLH-conjugated synthetic peptide between 48-79 amino acids from the N-terminal region of human PIASy.

PurityPurified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Appearance/FormLiquid

FormulationPBS containing 0.09% sodium azide.

StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Regulatory StatusResearch Use Only

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