EAAT2 antibody,Genetex,GTX37432

Host

Rabbit

Reactivity

Rat

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB521551588

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameEAAT2 antibody
Cat. No.GTX37432
Gene ID (Entrez)6506
HostRabbit
IsotypeIgG
ReactivityRat
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSLC1A2
ImmunogenKLH conjugated synthetic peptide derived between 111-190 amino acids of human EAAT2
PurityProtein A purified
Appearance/FormLiquid
Formulation10mM TBS, 0.5% BSA, 25% Glycerol,0.015% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]

Synonyms

solute carrier family 1 member 2 , EAAT2 , EIEE41 , GLT-1 , HBGT

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