EDA-A2 antibody [3T2],Genetex,GTX52707

The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ECTD1 , ED1 , ED1A1 , ED1A2 , EDA , EDA1 , EDA2 , EDAA1 , EDAA2 , HED , HED1 , ODT1 , STHAGX1 , TNLG7C , XHED , XLHED , ectodysplasin A , Ectodysplasin A