EGFR antibody [EGFR.113],Genetex,GTX01874

Host

Mouse

Reactivity

Human

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB093400877

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameEGFR antibody [EGFR.113]
Cat. No.GTX01874
Gene ID (Entrez)1956
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P
ClonalityMonoclonal
TargetEGFR
ImmunogenProkaryotic fusion protein corresponding to the external domain of the epidermal growth factor receptor molecule.
PurityUnpurified
Appearance/FormLiquid
FormulationTissue culture supernatant,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Synonyms

epidermal growth factor receptor , ERBB , ERBB1 , HER1 , NISBD2 , PIG61 , mENA

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