EIF3A antibody [N1N2], N-term,Genetex,GTX118895

Host

Rabbit

Reactivity

Human

Application

WB ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB642527285

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameEIF3A antibody [N1N2], N-term
Cat. No.GTX118895
Gene ID (Entrez)8661
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityPolyclonal
Concentration0.96 mg/ml (Please refer to the vial label for the specific concentration.)
TargetEIF3A
ImmunogenRecombinant protein encompassing a sequence within the N-terminus region of human EIF3A. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 1% BSA, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Synonyms

eukaryotic translation initiation factor 3 subunit A , EIF3 , EIF3S10 , P167 , TIF32 , eIF3-p170 , eIF3-theta , p180 , p185

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