EP300 antibody [RW128],Genetex,GTX30614

Host

Mouse

Reactivity

Human, Mouse, Rat, Mustelid, Primate

Application

WB ICC/IF FCM IP

Conjugate

Unconjugated

Platform ID

BAB498262772

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameEP300 antibody [RW128]
Cat. No.GTX30614
Gene ID (Entrez)2033
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat, Mustelid, Primate
ConjugationUnconjugated
ApplicationWB ICC/IF FCM IP
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetEP300
ImmunogenFusion protein containing residues 1572-2371 of human KAT3B/p300. [UniProt# Q0947]
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq]

Synonyms

E1A binding protein p300 , KAT3B , MKHK2 , RSTS2 , p300

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.