EPO receptor antibody [6A33],Genetex,GTX52803

Host

Mouse

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB997901681

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameEPO receptor antibody [6A33]
Cat. No.GTX52803
Gene ID (Entrez)2057
HostMouse
IsotypeIgG2
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityMonoclonal
Concentration200 μg/ml (Please refer to the vial label for the specific concentration.)
TargetEPOR
ImmunogenRecombinant Human EPO R
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Synonyms

EPOR , erythropoietin receptor , EPO receptor

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