ERCC8 Recombinant Antibody,Bioss,bsm-62393r-100ul
Host
Rabbit
Reactivity
Human
Application
WB, IP
Conjugate
Unconjugated
Platform ID
BAB193538764
Bioss
Contact
Tel: +1.781.569.5821
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Product Specifications
Scientific Background
Synonyms
Specifications
NameERCC8 Recombinant Antibody
Cat. No.bsm-62393r-100ul
Accession NumberQ13216
Gene ID (Entrez)1161
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IP
Working DilutionsWB:1:500-2000 | IP:IP1:20-50
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Scientific Background
Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair.
Synonyms
CKN1; CSA; ERCC8.
Category Paths
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Primary Antibodies>IHC Antibodies
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