EVI1 antibody, Internal,Genetex,GTX88191

Host

Goat

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB144742428

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameEVI1 antibody, Internal
Cat. No.GTX88191
HostGoat
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration0.50 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenPeptide with sequence C-DKESLHSTSH, from the internal region of the protein sequence according to NP_001098547.3; NP_005232.2; NP_004982.2; NP_001157471.1; NP_001157472.1.
PurityPurified by ammonium sulphate precipitation followed by antigen affinity chromatography
Appearance/FormLiquid
FormulationTBS, 0.5% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Synonyms

Mds1 And Evi1 Complex Locus , Aml1-Evi-1 , Evi1 , Kmt8E , Mds1 , Mds1-Evi1 , Prdm3 , Rusat2 , Mecom

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