Endothelin 1 antibody [TR.ET.48.5],Genetex,GTX22786

Host

Mouse

Reactivity

Human, Mouse, Rat, Sheep, Dog, Pig

Application

WB ICC/IF IHC-P IHC-Fr FCM RIA

Conjugate

Unconjugated

Platform ID

BAB801173627

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameEndothelin 1 antibody [TR.ET.48.5]
Cat. No.GTX22786
Gene ID (Entrez)1906
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat, Sheep, Dog, Pig
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr FCM RIA
ClonalityMonoclonal
Concentration2.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetEDN1
ImmunogenPure endothelin-1 conjugated to KLH.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Synonyms

endothelin 1 , ARCND3 , ET1 , HDLCQ7 , PPET1 , QME

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