Estrogen Receptor beta Rabbit mAb,ABclonal,A26153

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, IF-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB347744940

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameEstrogen Receptor beta Rabbit mAb
Cat. No.A26153
Accession NumberQ92731
Gene ID (Entrez)2100
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, IF-P, ELISA
Working DilutionsWB:1:1000 - 1:5000 | IF/ICC:1:50 - 1:200 | IF-P:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC67956
Molecular Weight50-60kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

Synonyms

Erb; ESRB; ODG8; ESTRB; NR3A2; ER-BETA; ESR-BETA

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