Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) Antibody,Abbexa,abx025627

Name: Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) Antibody,Abbexa,abx025627
Brand: Buy Antibody
SKU: BAB081130678

EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB

Conjugate

Unconjugated

Platform ID

BAB081130678

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

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Product Specifications

NameEuchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) Antibody

Cat. No.abx025627

Accession NumberQ9H9B1

HostRabbit

IsotypeIgG

ReactivityHuman

ConjugationUnconjugated

ApplicationELISA, WB

Working DilutionsWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.

ClonalityPolyclonal

Molecular WeightCalculated MW: 141 kDa

ImmunogenKLH-conjugated synthetic peptide between 203-233 amino acids from the N-terminal region of human EHMT1.

PurityPurified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Appearance/FormLiquid

FormulationPBS containing 0.09% sodium azide.

StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Regulatory StatusResearch Use Only

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