Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibody,Abbexa,abx031230
EIF4EBP1 is one member of a family of translation repressor proteins. It directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Host
Rabbit
Reactivity
Human
Application
ELISA, WB, IHC
Conjugate
Unconjugated
Platform ID
BAB986609863
Abbexa
Contact
Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951
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Product Specifications
Specifications
NameEukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibody
Cat. No.abx031230
Accession NumberQ13541
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB, IHC
Working DilutionsWB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 12.6 kDa
ImmunogenKLH-conjugated synthetic peptide between 48-77 amino acids from human EIF4EBP1.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Polyclonal Antibodies
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