Exonuclease 5 antibody,Genetex,GTX53538

Host

Rabbit

Reactivity

Human, Mouse, Hamster

Application

WB FCM

Conjugate

Unconjugated

Platform ID

BAB939318550

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameExonuclease 5 antibody
Cat. No.GTX53538
Gene ID (Entrez)64789
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Hamster
ConjugationUnconjugated
ApplicationWB FCM
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetEXO5
ImmunogenKLH conjugated synthetic peptide between 166-193 amino acids from the Central region of human DEM1.
PurityProtein A purified, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. [provided by RefSeq, Nov 2016]

Synonyms

exonuclease 5 , C1orf176 , DEM1 , Exo V , hExo5

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