Ezrin antibody [N2C2], Internal,Genetex,GTX111709

Host

Rabbit

Reactivity

Human, Mouse, Rat, Zebrafish

Application

WB ICC/IF IHC-P IHC-Wm

Conjugate

Unconjugated

Platform ID

BAB627634437

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameEzrin antibody [N2C2], Internal
Cat. No.GTX111709
Gene ID (Entrez)7430
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Zebrafish
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Wm
ClonalityPolyclonal
Concentration1.84 mg/ml (Please refer to the vial label for the specific concentration.)
TargetEZR
ImmunogenRecombinant protein encompassing a sequence within the center region of human Ezrin. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq]

Synonyms

ezrin , CVIL , CVL , HEL-S-105 , VIL2

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