FADD antibody [1C11],Genetex,GTX84542

Host

Mouse

Reactivity

Human

Application

WB FCM

Conjugate

Unconjugated

Platform ID

BAB821341413

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameFADD antibody [1C11]
Cat. No.GTX84542
Gene ID (Entrez)8772
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB FCM
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetFADD
ImmunogenFull length human recombinant protein of human FADD (NP_003815) produced in HEK293T cell.
PurityPurified by affinity chromatographyFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Synonyms

Fas associated via death domain , GIG3 , MORT1

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