FAP antibody,Genetex,GTX41169

Host

Rabbit

Reactivity

Human

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB713893013

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameFAP antibody
Cat. No.GTX41169
Gene ID (Entrez)2191
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetFAP
ImmunogenSynthetic peptide: extracellular domain of human FAP alpha, conjugated to keyhole limpet hemocyanin.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

Synonyms

fibroblast activation protein alpha , DPPIV , FAPA , FAPalpha , SIMP

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