FBP1 Antibody (YA1264),MedChemexpress,HY-P81519

The FBP1 protein is a key enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate, playing a crucial role as a rate-limiting enzyme in gluconeogenesis. Its enzymatic activity is facilitated by divalent cations. FBP1 is integral to the regulation of glucose homeostasis and insulin secretion in pancreatic beta-cells, influencing glucose sensing. Additionally, FBP1 is implicated in the modulation of glycerol gluconeogenesis in the liver. Notably, this protein serves as a significant regulator of appetite and adiposity, as increased expression in the liver following nutrient excess leads to elevated levels of circulating satiety hormones and a reduction in appetite-stimulating neuropeptides. This suggests that FBP1 acts as a feedback mechanism to limit weight gain in response to nutritional abundance.

6-bisphosphatase 1 antibody; 6-bisphosphate 1-phosphohydrolase 1 antibody; D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody; D-fructose-1 antibody; EC 3.1.3.11 antibody; F16P1_HUMAN antibody; FBP antibody; FBP 1 antibody; FBP1 antibody; FBPase 1 antibody; Fructose 1 6 bisphosphatase 1 antibody; Fructose bisphosphatase 1 antibody; Fructose-1 antibody; Growth inhibiting protein 17 antibody; Liver fructose bisphosphatase antibody;