FDPS Antibody (YA2817),MedChemexpress,HY-P83072

FDPS Antibody (YA2817) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FDPS.

Host

Rabbit

Reactivity

Human,Hamster

Application

WB,IHC-P

Conjugate

Non-conjugated

Platform ID

BAB767660067

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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Contact

Tel: 609-228-6898
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Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameFDPS Antibody (YA2817)
Cat. No.HY-P83072
Accession NumberP14324
Gene ID (Entrez)2224
HostRabbit
RRIDAB_3105187
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Hamster
ConjugationNon-conjugated
ApplicationWB,IHC-P
Working DilutionsWB: 1:500-1:1000; IHC-P: 1:50-1:100
ClonalityRecombinant,Monoclonal
Clone NumberYA2817
Molecular WeightPredicted band size: 48 kDa; Observed band size: 48 kDa
ImmunogenA synthetic peptide of human FDPS
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

The related gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit The enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudorelated genes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for The related gene.

Synonyms

FPS; FPPS; POROK9

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