FITC Anti-CCR5 antibody [HEK/1/85a],Abcam,AB11466

This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Host

Rat

Reactivity

Human, Rat, Mouse

Application

IHC-Fr, Flow Cyt

Conjugate

FITC

Platform ID

BAB117154297

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameFITC Anti-CCR5 antibody [HEK/1/85a]
Cat. No.AB11466
HostRat
IsotypeIgG2a
ReactivityHuman, Rat, Mouse
ConjugationFITC
ApplicationIHC-Fr, Flow Cyt
ClonalityMonoclonal
Clone NumberHEK/1/85a
Concentration0.1 mg/mL Batch dependent concentration
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.09% Sodium azide Constituents: PBS, 1% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor (PubMed : 30713770).. (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1. See full target information CCR5

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