FITC Anti-CD10 antibody [MEM-78],Abcam,AB28096

The antibody is free of unconjugated FITC.

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

FITC

Platform ID

BAB054673038

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameFITC Anti-CD10 antibody [MEM-78]
Cat. No.AB28096
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationFITC
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberMEM-78
ImmunogenCell preparation containing MME protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: 0.2% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed : 15283675, PubMed : 6208535, PubMed : 6349683, PubMed : 8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed : 17101991, PubMed : 6349683). Catalyzes cleavage of bradykinin, substance P and neurotensin peptides (PubMed : 6208535). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed : 15283675, PubMed : 6349683). Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)) (PubMed : 16254193, PubMed : 2531377, PubMed : 2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed : 20876573). See full target information MME

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