FITC Anti-CD55 antibody [MEM-118],Abcam,AB28112

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

FITC

Platform ID

BAB680385196

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameFITC Anti-CD55 antibody [MEM-118]
Cat. No.AB28112
HostMouse
IsotypeIgM
ReactivityHuman
ConjugationFITC
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberMEM-118
ImmunogenCell preparation containing CD55 protein. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 8 Preservative: 0.097% Sodium azide Constituents: Tris buffered saline, 0.2% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed : 7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed : 28657829).. (Microbial infection) Acts as a receptor for Coxsackievirus A21, coxsackieviruses B1, B3 and B5.. (Microbial infection) Acts as a receptor for Human enterovirus 70 and D68 (Probable).. (Microbial infection) Acts as a receptor for Human echoviruses 6, 7, 11, 12, 20 and 21. See full target information CD55

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