FITC Anti-CD83 antibody [Michel-19],Abcam,AB48318

Conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

Host

Rat

Application

Flow Cyt

Conjugate

FITC

Platform ID

BAB868128829

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameFITC Anti-CD83 antibody [Michel-19]
Cat. No.AB48318
HostRat
IsotypeIgG1
ConjugationFITC
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberMichel-19
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Mouse Cd83.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHC II trafficking MARCHF8 (PubMed : 27503071, PubMed : 27503069). Also inhibits MARCHF1 association with MHC II and ubiquitination of MHCII (By similarity). In addition, acts as an important modulator of protective responses against acute infections (PubMed : 31527313). See full target information Cd83

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