FITC Anti-CTLA4 antibody [1B8],Abcam,AB24935
Host
Armenian hamster
Reactivity
Mouse
Application
Flow Cyt
Conjugate
FITC
Platform ID
BAB305797498
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameFITC Anti-CTLA4 antibody [1B8]
Cat. No.AB24935
HostArmenian hamster
IsotypeIgG
ReactivityMouse
ConjugationFITC
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number1B8
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human CTLA4.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Inhibitory receptor acting as a major negative regulator of T-cell responses (PubMed : 11279501, PubMed : 11279502, PubMed : 16551244, PubMed : 1714933, PubMed : 18641304, PubMed : 28484017). Acts as a decoy receptor : the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28 (PubMed : 11279501, PubMed : 11279502, PubMed : 16551244, PubMed : 1714933, PubMed : 28484017). See full target information CTLA4
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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