FITC Anti-Ctip2 antibody [25B6],Abcam,AB123449

What is this antibody validated in? FITC Anti-Ctip2 antibody [25B6] (ab123449) is a rat monoclonal antibody and is validated for use in Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. Related products Antibody clone 25B6 is also available pre-conjugated to a variety of labels for your convenience – Anti-Ctip2 FITC [25B6] (ab123449). Other related products We have a range of other formats of antibody clone [25B6] also available for your convenience: ab18465 , FITC - ab123449

Host

Rat

Reactivity

Human

Application

Flow Cyt (Intra), ICC/IF

Conjugate

FITC

Platform ID

BAB993291251

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameFITC Anti-Ctip2 antibody [25B6]
Cat. No.AB123449
HostRat
IsotypeIgG2a
ReactivityHuman
ConjugationFITC
ApplicationFlow Cyt (Intra), ICC/IF
ClonalityMonoclonal
Clone Number25B6
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityPrecipitation Ammonium Sulphate
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (PubMed : 27959755). Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes (PubMed : 16809611). Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). May also function in the P53-signaling pathway (By similarity). See full target information BCL11B

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