FITC Anti-IL-2 Receptor alpha antibody [PC61.5],Abcam,AB210332

ab210332 is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used to distinguish Treg cells from naïve or conventional T cells which are CD25-. This clone has also been reported for depletion of Treg cells in vivo.

Host

Rat

Reactivity

Mouse

Application

Flow Cyt

Conjugate

FITC

Platform ID

BAB118853481

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameFITC Anti-IL-2 Receptor alpha antibody [PC61.5]
Cat. No.AB210332
HostRat
IsotypeIgG1
ReactivityMouse
ConjugationFITC
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberPC61.5
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. See full target information Il2ra

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