FITC Anti-Myeloperoxidase antibody [2D4],Abcam,AB90812

What is this antibody validated in? FITC Anti-Myeloperoxidase antibody [2D4] (ab90812) is a mouse monoclonal antibody and is validated for use in Flow Cytometry (Intra), Flow Cytometry (Flow Cyt) in Mouse, Rat samples. Trusted by the scientific community Anti-Myeloperoxidase [2D4] FITC (ab90812) was first used in a scientific publication in 2010 and has been cited over 20 times in peer-reviewed journals. Related products Antibody clone 2D4 is also available pre-conjugated to a variety of labels for your convenience – Anti-Myeloperoxidase FITC [2D4] (ab90812). Other related products We have a range of other formats of antibody clone [2D4] also available for your convenience: ab90810 , FITC - ab90812

Host

Mouse

Reactivity

Mouse, Rat

Application

Flow Cyt (Intra)

Conjugate

FITC

Platform ID

BAB244415711

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameFITC Anti-Myeloperoxidase antibody [2D4]
Cat. No.AB90812
HostMouse
IsotypeIgG1
ReactivityMouse, Rat
ConjugationFITC
ApplicationFlow Cyt (Intra)
ClonalityMonoclonal
Clone Number2D4
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed : 9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed : 25698971). See full target information MPO

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