FITC Anti-Tissue Plasminogen Activator antibody,Abcam,AB28376

Host

Rabbit

Reactivity

Human

Application

ELISA

Conjugate

FITC

Platform ID

BAB182534164

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameFITC Anti-Tissue Plasminogen Activator antibody
Cat. No.AB28376
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationFITC
ApplicationELISA
ClonalityPolyclonal
Concentration4.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human PLAT.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.6 Constituents: 0.82% Sodium phosphate, 0.58% Sodium chloride, 0.0292% EDTA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy (By similarity). See full target information PLAT

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