FITC Anti-Vimentin antibody [RV202],Abcam,AB128507

Host

Mouse

Reactivity

Human, Pig

Application

Flow Cyt (Intra), IHC-Fr

Conjugate

FITC

Platform ID

BAB120152857

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameFITC Anti-Vimentin antibody [RV202]
Cat. No.AB128507
HostMouse
IsotypeIgG1
ReactivityHuman, Pig
ConjugationFITC
ApplicationFlow Cyt (Intra), IHC-Fr
ClonalityMonoclonal
Clone NumberRV202
Concentration0.028 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Cow VIM.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.09% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Plays a role in cell directional movement, orientation, cell sheet organization and Golgi complex polarization at the cell migration front (By similarity). Protects SCRIB from proteasomal degradation and facilitates its localization to intermediate filaments in a cell contact-mediated manner (By similarity). May promote axon outgrowth and motor fiber repair via DSP-mediated recruitment to outgrowth tips (By similarity).. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. See full target information VIM

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