FITC Rabbit anti-Dog CD45 mAb,ABclonal,A28701
Reactivity
Dog
Application
FC
Conjugate
FITC. Ex:491nm. Em:516nm.
Platform ID
BAB501582327
ABclonal
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Product Specifications
Scientific Background
Specifications
NameFITC Rabbit anti-Dog CD45 mAb
Cat. No.A28701
RRID#N/A
IsotypeIgG
ReactivityDog
ConjugationFITC. Ex:491nm. Em:516nm.
ApplicationFC
Working DilutionsFC:≤0.25 µg per million cells in 100 µl volume
Clone NumberARC81636
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at 2-8℃. Avoid freeze.; Buffer: PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
CD45 (leukocyte common antigen, PTPRC) is a transmembrane protein tyrosine phosphatase that is widely expressed on the surface of all nucleated hematopoietic cells (T cells, B cells, NK cells, etc.). Its core functions include: regulation of immune cell ctivation: By dephosphorylating the inhibitory sites of Src kinases (such as Lck and Fyn), it activates the T-cell receptor (TCR) and B-cell receptor (BCR) signaling pathways. Maintenance of immune tolerance: Regulating thymocyte development and the clearance of autoreactive lymphocytes.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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