FITC anti-human CD108 Antibody, CD108, KS-2,BioLegend,376605

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB367757858

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameFITC anti-human CD108 Antibody, CD108, KS-2
Cat. No.376605
HostMouse
RRIDAB_3068240 (BioLegend Cat. No. 376605)AB_3068240 (BioLegend Cat. No. 376606)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberKS-2
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD108
ImmunogenPHA-activated PBMC
PurityThe antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD108 is an 80 kD GPI-linked membrane-bound semaphorin, also known as the John-Milton-Hagen (JMH) blood group antigen, semaphorin 7A, H-SEMA, and SEMAL. It contains an Ig-like domain and is expressed at low levels on erythrocytes and lymphocytes. The expression of CD108 on lymphocytes is upregulated upon activation, and it plays an important role in modulating inflammation and T-cell-mediated immune responses. CD108 is a guidance protein that is involved in central and peripheral axon growth. The interaction of CD108 with its receptor PlexinC1 induces activation of monocytes.

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