FITC anti-human CD159c (NKG2C) Antibody, CD159c (NKG2C), S19005E,BioLegend,375021

S19005E does not crossreact with mouse CD159c.

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB884188703

BioLegend

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Contact

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Product Specifications
Scientific Background

Specifications

NameFITC anti-human CD159c (NKG2C) Antibody, CD159c (NKG2C), S19005E
Cat. No.375021
HostMouse
RRIDAB_3683404 (BioLegend Cat. No. 375021)AB_3683404 (BioLegend Cat. No. 375022)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberS19005E
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD159c
ImmunogenHuman NKG2C/CD94-transfectants
PurityThe antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD159c, also known as NKG2C or KLRC2, is a type II transmembrane protein. It belongs to the killer cell lectin-like receptor family also known as the NKG2 family. It is expressed on NK and NKT cells and T cell subsets. NKG2C is an activating NK cell receptor and it is expressed as a heterodimer with CD94. In humans, the NKG2C/CD94 complex interacts with HLA-E on target cells and delivers activating signals through immunoreceptor tyrosine-based activation motifs.

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