FITC anti-human CD294 (CRTH2) Recombinant Antibody, CD294, QA20A89,BioLegend,379805

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB895294634

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameFITC anti-human CD294 (CRTH2) Recombinant Antibody, CD294, QA20A89
Cat. No.379805
HostMouse
RRIDAB_3097324 (BioLegend Cat. No. 379805)AB_3097324 (BioLegend Cat. No. 379806)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityRecombinant
Clone NumberQA20A89
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD294
PurityThe antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD294, also known as CRTH2, is a seven-transmembrane protein coupled with heterotrimeric G proteins. CRTH2 is the prostaglandin D2 receptor and is expressed by Th2 cells, eosinophils, and basophils. CD294 prevents the apoptosis of Th2 cells and mediates the chemotaxis of CRTH2 expressing cells to the sites of allergic inflammation, such as the asthmatic lung.

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