FITC anti-human CD305 (LAIR1) Antibody, CD305, NKTA255,BioLegend,342814
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB340548396
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameFITC anti-human CD305 (LAIR1) Antibody, CD305, NKTA255
Cat. No.342814
HostMouse
RRIDAB_3662239 (BioLegend Cat. No. 342813)AB_3662239 (BioLegend Cat. No. 342814)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberNKTA255
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD305
PurityThe antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD305, also known as LAIR-1 (leukocyte-associated Ig-like receptor-1), is a 40 kD type I transmembrane glycoprotein. LAIR-1 and LAIR-2 are the only members of the LAIR family in the Ig superfamily. LAIR-1 is an inhibitory molecule characterized by ITIMs in the cytoplasmic domain and collagen ligands. CD305 is expressed on NK cells, T cells, B cells, monocytes, dendritic cells, eosinophils, basophils and mast cells. LAIR-1 functions in the inhibition of cell cytotoxicity, cell activation, proliferation and differentiation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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