FITC anti-human KLRG1 MAFA Antibody anti-KLRG1 - SA231A2,BioLegend,367714
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB888686543
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameFITC anti-human KLRG1 MAFA Antibody anti-KLRG1 - SA231A2
Cat. No.367714
HostMouse
RRIDAB_2572158 (BioLegend Cat. No. 367713)AB_2572159 (BioLegend Cat. No. 367714)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberSA231A2
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetKLRG1
ImmunogenHuman KLRG1-transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibititory motif (ITIM). KLRG1 is expressed by subsets of NK, effector and memory T cells. KLRG1 inhibits cell activation and proliferation, and is a marker of T cell senescence. Binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of Akt and increases the expression of cell cycle inhibitors.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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