FITC anti-human TCR Vbeta5 related subset Antibody anti-TCR V beta 5 - MEM-262,BioLegend,316704

Additional reported applications (for the relevant formats) include: immunoprecipitation, Western blotting, and activation of T cells Vß5 related subset.

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB652954691

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Product Specifications
Scientific Background

Specifications

NameFITC anti-human TCR Vbeta5 related subset Antibody anti-TCR V beta 5 - MEM-262
Cat. No.316704
HostMouse
RRIDAB_528957 (BioLegend Cat. No. 316704)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberMEM-262
ConcentrationLot-specific (to obtain lot-specific concentration, please enter the lot number in ourConcentration and Expiration LookuporCertificate of Analysisonline tools.)
TargetTCR Vbeta5
ImmunogenHuman thymoma cell line HPB-ALL
PurityThe antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The Vβ5 TCR is a variant of the TCR β chain. It belongs to Ig superfamily and is expressed by a subset of peripheral blood T cells and some T cell clones. TCR Vβ5 has been reported to recognize some staphylococcus bacterial superantigens. MEM-262 antibody reacts with a variant of the TCR β chain which is expressed on HPB-ALL cells (known expressing TCR Vβ5.3). But the subpopulation of peripheral blood T cells recognized by this antibody is reported larger than other anti-TCR Vβ5.3 antibodies.

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