FITC anti-mouse CD20 Recombinant Antibody, CD20, QA18A73,BioLegend,161410
This recombinant antibody clone is derived from clone SA271G2.
Host
Mouse
Reactivity
Mouse
Application
FC - Qulaity tested
Platform ID
BAB563686296
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameFITC anti-mouse CD20 Recombinant Antibody, CD20, QA18A73
Cat. No.161410
HostMouse
RRIDAB_3097401 (BioLegend Cat. No. 161409)AB_3097401 (BioLegend Cat. No. 161410)
IsotypeMouse IgG2a, κ
ReactivityMouse
ApplicationFC - Qulaity tested
ClonalityRecombinant
Clone NumberQA18A73
Concentration0.5 mg/mL
TargetCD20
ImmunogenMouse CD20 transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD20 is a 33-37 kD protein, a member of the MS4A family, with four transmembrane spanning regions that present as a homo-oligomeric complexes in the cell surface when associating with MHC class I and II, CD53, CD81, and CD82. CD20 is expressed on B cells and a subset of T cells, but not on plasma cells. CD20 regulates B-cell activation and proliferation. Its ligation promotes transmembrane Ca2+ trafficking. CD20 is an important therapeutic target in the treatment of B cell lymphomas and leukemias.
Category Paths
- Products>Primary Antibodies>Recombinant Antibodies
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