FITC anti-mouse CD335 NKp46 Antibody anti-CD335 - 29A1.4,BioLegend,137605
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue sections1,2andin vitroactivation of NK cells1.
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB486834467
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameFITC anti-mouse CD335 NKp46 Antibody anti-CD335 - 29A1.4
Cat. No.137605
HostRat
RRIDAB_2149150 (BioLegend Cat. No. 137605)AB_2298210 (BioLegend Cat. No. 137606)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number29A1.4
Concentration0.5 mg/ml
TargetCD335
ImmunogenNKP46-IgG1 Fc fusion protein
PurityThe antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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