FITC anti-mouse CD64 (FcγRI) Antibody, CD64, W18349C,BioLegend,164406

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB457614706

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameFITC anti-mouse CD64 (FcγRI) Antibody, CD64, W18349C
Cat. No.164406
HostRat
RRIDAB_3068115 (BioLegend Cat. No. 164405)AB_3068115 (BioLegend Cat. No. 164406)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW18349C
Concentration0.5 mg/mL
TargetCD64
ImmunogenRecombinant mouse FcƳRI/CD64 (aa 25-297)
PurityThe antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcRI. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and mast cells. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

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