FITC anti-mouse CD69 Antibody anti-CD69 - H1.2F3,BioLegend,104505

The H1.2F3 antibody has been reported to augment T cell activation. Additional reported applications (for the relevant formats) include:in vitroT cell and NK cell activation1-3, immunohistochemistry4,5, and immunoprecipitation1.This antibody has been characterized in the literature as containing a lambda light chain.

Host

Armenian Hamster

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB413946941

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameFITC anti-mouse CD69 Antibody anti-CD69 - H1.2F3
Cat. No.104505
HostArmenian Hamster
RRIDAB_313108 (BioLegend Cat. No. 104505)AB_313109 (BioLegend Cat. No. 104506)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberH1.2F3
Concentration0.5 mg/ml
TargetCD69
ImmunogenMouse dendritic epidermal T cell line Y245
PurityThe antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD69 is a 60 kD type II membrane protein composed of a 27/33 kD disulfide-linked homodimer, also known as Very Early Activation Antigen (VEA), AIM, EA1, MLR3, and gp34/28. It is expressed on a subset of thymocytes and platelets. CD69 is rapidly induced on activated T and B cells, neutrophils, and NK cells. It is a C-type lectin, closely related to the NKR-P1 and Ly-49 NK cell activation molecules. CD69 is involved in the early events of cell activation and thymocyte positive selection.

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