FITC anti-mouse TCR γ/δ Recombinant Antibody, TCR γ/δ, QA20A16,BioLegend,107304
Clone QA20A16 is able to completely block the staining of clone GL3 on target cells.
Host
Mouse
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB457426061

BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Specifications
Scientific Background
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The γ/δ TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8- although some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation.
Category Paths
- Products>Primary Antibodies>Recombinant Antibodies
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