FITC anti-mouse TCR Vγ4 Antibody, TCR Vγ4, 49.2,BioLegend,160606

T cell receptor (TCR) is a heterodimer consisting of an α and β chain (TCR α/β) or a γ and δ chain (TCR γ/δ). TCR associates with CD3 to form a CD3/TCR complex. The CD3/TCR plays a key role in antigen recognition, signal transduction, and T cell activation. γδ T cells (gamma delta T cells) are a small subset of T cells that express a unique TCR. They are found in the thymus, peripheral lymphoid tissue, and peritoneum. Unlike αβ T cells, γδ T cells do not require antigen processing in order to recognize certain bacterial, lipid, and tumor antigens.The 49.2 antibody reacts specifically with mouse TCR Vγ4 as designated by Heilig/Tonegawa nomenclature.2Mouse TCR Vγ4 is also known as TCR Vγ2 under the Garman nomenclature system. Several TCR γ and δ chain nomenclature systems exist.In order to consolidate the various nomenclature systems, we have created charts for corresponding names across some of the most popular naming methods.Clickhereto see charts.