FITC anti-mouse TCR Vbeta11 Antibody anti-TCR V beta 11 - KT11,BioLegend,125905

Host

Rat

Reactivity

Mouse

Application

FC -Quality tested

Platform ID

BAB805326575

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameFITC anti-mouse TCR Vbeta11 Antibody anti-TCR V beta 11 - KT11
Cat. No.125905
HostRat
RRIDAB_1227780 (BioLegend Cat. No. 125905)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberKT11
Concentration0.5 mg/ml
TargetTCR Vbeta11
PurityThe antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The Vβ11 gene locus is deleted in mice of TCR a haplotype (C57BR, C57L, SJL, SWR) and TCR c haplotype (RIII).Mice of TCR b haplotype (C57BL, BALB/c, AKR, etc) have Vβ11-bearing T cells .However, mice expressing MHC class II I-E and some superantigens, such as Mtv-8, Mtv-9 and Mtv-11 will show a partial deletion of Tb11-bearing T cells.

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