FITC anti-mouse TCR vβ8.3 Antibody, TCR vbeta8.3, 1B3.3,BioLegend,156305
Clone 1B3.3 recognizes TCR vß8.3 from both C57BL/6 and BALB/c strains.
Host
Armenian Hamster
Reactivity
Mouse
Application
FC -Quality tested
Platform ID
BAB794742922
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameFITC anti-mouse TCR vβ8.3 Antibody, TCR vbeta8.3, 1B3.3
Cat. No.156305
HostArmenian Hamster
RRIDAB_2800701 (BioLegend Cat. No. 156305)AB_2800702 (BioLegend Cat. No. 156306)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number1B3.3
Concentration0.5 mg/ml
TargetTCR Vbeta8.3
Immunogen3.L2 T Cell Clone Expressing the vβ8.3 TCR
PurityThe antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The TCR Vβ8 family consists of three members, namely Vβ8.1, 8.2 and 8.3. 1B3.3 reacts with Vβ8.3 only, but not Vβ8.1 or Vβ8.2. Most mouse strains have about 20% Vβ8+ T cells in the periphery. However, C57BR, C57L, SJL, SWR (Tcra haplotype) and RIII strains (Tcrc haplotype) do not express Vβ8 due to a gene deletion at the Vβ8 loci. Exogenous superantigen, such as staphylococcal enterotoxin B, stimulates lymphocytes bearing Vβ8 and selectively eliminate those T cellsin vivo.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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