FKBP12 antibody [3B3],Genetex,GTX84492

Host

Mouse

Reactivity

Human, Dog

Application

WB IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB258710226

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameFKBP12 antibody [3B3]
Cat. No.GTX84492
Gene ID (Entrez)2280
HostMouse
IsotypeIgG2b
ReactivityHuman, Dog
ConjugationUnconjugated
ApplicationWB IHC-P FCM
ClonalityMonoclonal
Concentration0.8 mg/ml (Please refer to the vial label for the specific concentration.)
TargetFKBP1A
ImmunogenFull length human recombinant protein of human FKBP1A (NP_000792) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Synonyms

FKBP prolyl isomerase 1A , FKBP-12 , FKBP-1A , FKBP1 , FKBP12 , PKC12 , PKCI2 , PPIASE

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