FLIP antibody [5D8],Genetex,GTX53717

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB ELISA

Conjugate

Unconjugated

Platform ID

BAB252224605

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFLIP antibody [5D8]
Cat. No.GTX53717
Gene ID (Entrez)8837
HostMouse
IsotypeIgG3
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ELISA
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCFLAR
ImmunogenRecombinant human FLIP (1-376aa) purified from E. coli
PurityBy protein-G affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]

Synonyms

CASP8 and FADD like apoptosis regulator , CASH , CASP8AP1 , CLARP , Casper , FLAME , FLAME-1 , FLAME1 , FLIP , I-FLICE , MRIT , c-FLIP , c-FLIPL , c-FLIPR , c-FLIPS , cFLIP

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