FREM1 antibody,Genetex,GTX85179

Host

Rabbit

Reactivity

Human, Mouse

Application

WB ICC/IF ELISA

Conjugate

Unconjugated

Platform ID

BAB011283990

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFREM1 antibody
Cat. No.GTX85179
Gene ID (Entrez)158326
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetFREM1
ImmunogenFREM1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human FREM1.The immunogen is located within the last 50 amino acids of FREM1.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.

Synonyms

FRAS1 related extracellular matrix 1 , BNAR , C9orf143 , C9orf145 , C9orf154 , MOTA , TILRR , TRIGNO2

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